Japanese researchers find new substances that inhibit blood vessel aging

Researchers at Osaka University in Japan recently discovered that hepatocyte growth factor can inhibit vascular aging.
The Asahi Shimbun website recently reported that experts generally believe that the formation and regeneration of blood vessels are related to endothelial progenitor cells derived from the differentiation of myeloid cells. Once people have diabetes or high blood pressure, it is difficult for them to repair themselves after blood vessels are damaged. Researchers used high blood pressure patients as the research object and found that the reason why their blood vessels were difficult to repair was that the hormone Ang II, which causes hypertension, caused aging of endothelial progenitor cells and reduced the ability to repair. After investigating the experimental mice, the researchers found that hepatocyte growth factor can inhibit the effect of angiotensin II, thereby promoting the formation and regeneration of blood vessels. In addition, hepatocyte growth factor can also improve the blood circulation of experimental mice.
Researchers say that the blood vessels of people with diabetes or high blood pressure will gradually age and cause strokes and other diseases. This study shows that people can try to use hepatocyte proliferation factor to inhibit vascular aging and prevent stroke and other diseases.

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